| Horseshoes of a Zephyr | — | very rare | — | DMG |
| Horseshoes of a Zephyr | — | very rare | — | XDMG |
| Horseshoes of Speed | — | rare | — | DMG |
| Horseshoes of Speed | — | rare | — | XDMG |
| Hourglass | G | none | — | PHB |
| House of Cards | — | uncommon | — | BMT |
| Hunk of Cheese | FD | none | — | PHB |
| Hunter's Coat | LA | very rare | Yes | EGW |
| Hunting Trap | G | none | — | PHB |
| Hunting Trap | G|XPHB | none | — | XPHB |
| Icewind Dale Trinket | G | none | — | IDRotF |
| Icon of Ravenloft | — | legendary | by a creature of good alignment | CoS |
| Iggwilv's Cauldron | — | artifact | by a spellcaster | WBtW |
| Iggwilv's Horn | INS | rare | Yes | DitLCoT |
| Illuminator's Tattoo | — | common | Yes | TCE |
| Illusionist's Bracers | — | very rare | by a spellcaster | GGR |
| Immovable Rod | RD|DMG | uncommon | — | DMG |
| Immovable Rod | RD|XDMG | uncommon | — | XDMG |
| Infernal Amulet | — | rare | Yes | CoA |
| Infernal Plate Armor | HA | very rare | Yes | CoA |
| Infernal Puzzle Box | — | uncommon | — | BGDIA |
| Infernal Tack | — | legendary | by a creature of evil alignment. | MTF |
| Infiltrator's Key (Awakened) | — | — | — | EGW |
| Infiltrator's Key (Dormant) | — | legendary | Yes | EGW |
| Infiltrator's Key (Exalted) | — | — | — | EGW |
| Ingot of the Skold Rune | — | very rare | Yes | SKT |
| Ink | G|XPHB | none | — | XPHB |
| Ink (1-ounce bottle) | G | none | — | PHB |
| Ink Pen | G | none | — | PHB |
| Ink Pen | G|XPHB | none | — | XPHB |
| Insect Repellent (block of incense) | G | none | — | ToA |
| Insect Repellent (greasy salve) | G | none | — | ToA |
| Insignia of Claws | — | uncommon | — | HotDQ |
| Instrument of Illusions | — | common | — | XDMG |
| Instrument of Illusions | INS | common | Yes | XGE |
| Instrument of Scribing | — | common | — | XDMG |
| Instrument of Scribing | INS | common | Yes | XGE |
| Instrument of the Bards, Anstruth Harp | INS | very rare | by a bard | DMG |
| Instrument of the Bards, Anstruth Harp | — | very rare | by a bard | XDMG |
| Instrument of the Bards, Canaith Mandolin | INS | rare | by a bard | DMG |
| Instrument of the Bards, Canaith Mandolin | — | rare | by a bard | XDMG |
| Instrument of the Bards, Cli Lyre | INS | rare | by a bard | DMG |
| Instrument of the Bards, Cli Lyre | INS|XPHB | rare | by a bard | XDMG |
| Instrument of the Bards, Doss Lute | INS | uncommon | by a bard | DMG |
| Instrument of the Bards, Doss Lute | INS|XPHB | uncommon | by a bard | XDMG |
| Instrument of the Bards, Fochlucan Bandore | INS | uncommon | by a bard | DMG |
| Instrument of the Bards, Fochlucan Bandore | INS|XPHB | uncommon | by a bard | XDMG |
| Instrument of the Bards, Mac-Fuirmidh Cittern | INS | uncommon | by a bard | DMG |
| Instrument of the Bards, Mac-Fuirmidh Cittern | INS|XPHB | uncommon | by a bard | XDMG |
| Instrument of the Bards, Ollamh Harp | INS | legendary | by a bard | DMG |
