| Staff of Power | M|XPHB | very rare | by a sorcerer, warlock, or wizard | XDMG |
| Staff of Ruling | M | rare | Yes | QftIS |
| Staff of Striking | — | very rare | Yes | DMG |
| Staff of Striking | M|XPHB | very rare | Yes | XDMG |
| Staff of Swarming Insects | — | rare | by a bard, cleric, druid, sorcerer, warlock, or wizard | DMG |
| Staff of Swarming Insects | M|XPHB | rare | by a bard, cleric, druid, sorcerer, warlock, or wizard | XDMG |
| Staff of the Adder | — | uncommon | by a cleric, druid, or warlock | DMG |
| Staff of the Adder | M|XPHB | uncommon | Yes | XDMG |
| Staff of the Forgotten One | — | artifact | by a sorcerer, warlock, or wizard | ToA |
| Staff of the Ivory Claw | — | rare | by a spellcaster | EGW |
| Staff of the Magi | — | legendary | by a sorcerer, warlock, or wizard | DMG |
| Staff of the Magi | M|XPHB | legendary | by a sorcerer, warlock, or wizard | XDMG |
| Staff of the Python | — | uncommon | by a cleric, druid, or warlock | DMG |
| Staff of the Python | M|XPHB | uncommon | Yes | XDMG |
| Staff of the Rooted Hills | M | rare | Yes | BGG |
| Staff of the Woodlands | — | rare | by a druid | DMG |
| Staff of the Woodlands | M|XPHB | rare | by a druid | XDMG |
| Staff of Thunder and Lightning | — | very rare | Yes | DMG |
| Staff of Thunder and Lightning | M|XPHB | very rare | Yes | XDMG |
| Staff of Withering | — | rare | by a cleric, druid, or warlock | DMG |
| Staff of Withering | M|XPHB | rare | by a cleric, druid, or warlock | XDMG |
| Star Card | — | legendary | — | BMT |
| Star Moth | SPC|AAG | none | — | AAG |
| Star rose quartz | $G|DMG | none | — | DMG |
| Star rose quartz | $G|XDMG | none | — | XDMG |
| Star Ruby | $G|DMG | none | — | DMG |
| Star Ruby | $G|XDMG | none | — | XDMG |
| Star Sapphire | $G|DMG | none | — | DMG |
| Star Sapphire | $G|XDMG | none | — | XDMG |
| Statuette of Augury | — | unknown (magic) | — | PaBTSO |
| Statuette of Saint Markovia | OTH | unknown (magic) | — | CoS |
| Steel | M | very rare | by a good-aligned creature | WBtW |
| Steel Mirror | G | none | — | PHB |
| Stirring Dragon Vessel | — | rare | — | FTD |
| Stirring Dragon-Touched Focus | SCF | rare | — | FTD |
| Stirring Scaled Ornament | — | rare | — | FTD |
| Stone of Controlling Earth Elementals | — | rare | — | DMG |
| Stone of Controlling Earth Elementals | — | rare | — | XDMG |
| Stone of Creation | — | artifact | Yes | AitFR-AVT |
| Stone of Golorr | — | artifact | Yes | WDH |
| Stone of Good Luck | — | uncommon | Yes | DMG |
| Stone of Good Luck | — | uncommon | Yes | XDMG |
| Stone of Ill Luck | — | uncommon | Yes | TftYP |
| Stonebreaker's Breastplate | MA | legendary | Yes | BGG |
| Stonemaker War Pick | M | very rare | Yes | BMT |
| Stonespeaker Crystal | — | rare | Yes | OotA |
| Stonky's ring | RG|DMG | unknown (magic) | Yes | CM |
| Storm Boomerang | R | uncommon | — | PotA |
| Stormgirdle (Awakened) | — | — | — | EGW |
| Stormgirdle (Dormant) | — | legendary | Yes | EGW |
